Medication Gastroparesis Treatment
Domperidone: Available internationally but not FDA-approved in the US, domperidone stimulates stomach emptying and reduces nausea. It crosses the blood-brain barrier less than other prokinetic drugs.
For those who do not respond well or cannot tolerate the above medications, newer options that may be tried include: prucalopride (5-HT4 agonist) and eluxadoline (mixed opioid receptor agonist/antagonist). Treatment is individualized based on symptoms, underlying causes, and side effect profiles related to Gastroparesis Treatment .
Bethanechol: Works by stimulating the parasympathetic nervous system to promote GI motility. Common side effects are facial flushing and increased saliva production.
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