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The global 3D Cell Culture Market size is projected to reach a CAGR of 25.4% from 2023-2030.
A 3D cell culture is an in-vitro technique wherein the cells can grow in an artificially created environment. These environments closely resemble the architecture and functioning of the native tissue. 3D cell culture technique helps stimulate cell differentiation, proliferation, and migration by interacting with their three-dimensional surroundings as they would in the in-vivo environment. As 3D cell cultures can mimic the structure, activity, and microenvironment of the in-vivo tissues, this technique has varied applications in the fields of drug screening, regenerative medicine, stem cell therapies, cancer research, and cell biology.
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The extracellular matrix in 3D cell cultures enables cell–cell communication by direct contact as in an in-vivo environment by secreting cytokines and trophic factors. These factors are changed in a 2D environment that can significantly affect the cell–cell communication, which in turn can alter cell morphology and proliferation. As 2D cultures cannot recapitulate the architecture and complex cellular matrices as in 3D cultures, this technique is gaining popularity in the healthcare research sector.
Recent Developments
- In July 2021, Lonza Group AG (Switzerland) and CN Bio Innovations (UK) announced a distribution agreement providing pre-validated hepatocytes for use on CN Bio’s innovative PhysioMimix Organ-On-a-Chip (OOC) range of single and multi-organ micro physiological systems (MPS).
- In March 2021, Thermo Fisher Scientific Inc. (US) planned to spend around USD 600 million on expanding its bioprocessing production capabilities in the Americas, Europe, and Asia.
Prominent Players
· Merck KGaA
· Thermo Fisher Scientific, Inc.
· PromoCell GmbH
· Greiner Bio One International GmbH
· Corning, Inc.
· 3D Biomatrix
· Lonza
· Avantor Performance Materials, LLC
· Tecan Trading AG
· 3D Biotek LLC
· Global Cell Solutions, Inc.
· InSphero
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North America to Dominate the Market
- North America led the global market in 2021 and accounted for the highest revenue share.
- The region will retain its leading position throughout the forecast period on account of the availability of private and government funding for the development of advanced 3D cell culture models, high healthcare spending, and the presence of a large number of universities and research organizations investigating various stem cell-based approaches.
The 3D Cell Culture Market Segmentation:
On the basis of technology
· Scaffold-based 3D Cell Cultures
· Scaffold-free 3D Cell Cultures
· Bioreactors
On the basis of application
· Cancer
· Tissue Engineering & Immunohistochemistry
· Drug Development
· Stem Cell Research
· Others
On the basis of end-user
· Biotechnology and Pharmaceutical Industries
· Research Laboratories and Institutes
· Hospitals and Diagnostic Centres
· Others
Based on region:
· Asia Pacific
· North America
· Europe
· South America
· Middle East & Africa
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